Sanustan

Diagnostics

Advanced laboratory testing lets us look beneath symptoms to the systems driving them. Each evaluation brings together the conditions it clarifies, the full workup, and the laboratories chosen for the quality and depth of their testing.

Test descriptions are drawn from each laboratory's own website.

01

Comprehensive Blood Work

Comprehensive blood work is the foundation of every assessment. Measuring more than two hundred biomarkers across the heart, metabolism, hormones, nutrients, organ function and immunity reveals patterns a routine annual panel misses, often years before they become disease, and gives every specialty result its full context.

What We Evaluate

  • Heart and vascular health, including lipid particle size and number
  • Blood sugar, insulin and metabolic health
  • Thyroid, adrenal, female and male hormones
  • Vitamins, minerals, iron and omega fatty acids
  • Liver, kidney and pancreas function
  • Blood count and immune health
  • Inflammation and autoimmunity
  • Heavy metals
  • Complete urinalysis

Laboratories

Quest Diagnostics
Quest Diagnostics

Standard and Advanced Laboratory Testing

Blood and urine at any Quest location

More than 200 biomarkers across every major system, including advanced lipid particle testing and cardiac markers, drawn at any of more than 2,000 Quest locations nationwide.

View full test details
Quest DiagnosticsStandard and Advanced Laboratory Testing

Quest Diagnostics performs more than 200 million tests each year, with over 3,500 lab tests available and more than 2,000 patient service locations across the United States.

Heart & Vascular Health

A complete cardiovascular picture: lipids, particle number and size, arterial inflammation, heart strain and inherited risk.

  • Standard lipids: Total cholesterol, LDL, HDL, triglycerides, non-HDL cholesterol, remnant cholesterol
  • Apolipoproteins: Apolipoprotein B, apolipoprotein A1, ApoB/ApoA1 ratio, lipoprotein (a)
  • Particle number and size: LDL particle number, small and medium LDL particles, large HDL particles, LDL pattern, LDL peak size, small dense LDL cholesterol (Cardio IQ Ion Mobility)
  • Vascular inflammation: hs-CRP, homocysteine, Lp-PLA2 activity, myeloperoxidase (MPO), fibrinogen, microalbumin
  • Oxidative stress and endothelial function: Oxidized LDL, F2-isoprostanes, ADMA, SDMA, TMAO
  • Heart muscle: NT-proBNP, high sensitivity troponin T, galectin-3
  • Genetics: Apolipoprotein E (APOE) genotype
  • Risk ratios: Cholesterol/HDL, LDL/HDL, atherogenic index of plasma, Castelli risk indices
Metabolic Health

Glucose control and insulin resistance, often measurable years before diabetes.

  • Blood sugar: Fasting glucose, hemoglobin A1c, estimated average glucose, fructosamine
  • Insulin: Fasting insulin, C-peptide, HOMA-IR, Cardio IQ Insulin Resistance Score
  • Metabolic hormones: Leptin, adiponectin
  • Metabolic indices: Triglyceride/HDL ratio, TyG index, uric acid
Hormones

Thyroid, adrenal, sex and growth hormones, measured for how they are produced, balanced and converted.

  • Thyroid: TSH, free T4, free T3, total T4, total T3, reverse T3, T3 uptake, free thyroxine index
  • Thyroid antibodies: TPO antibodies, thyroglobulin antibodies, thyroglobulin, thyroid stimulating immunoglobulin
  • Adrenal and stress: Cortisol (AM), ACTH, DHEA-sulfate, pregnenolone
  • Female hormones: Estradiol, estrone, progesterone, FSH, LH, prolactin, anti-Mullerian hormone (AMH), SHBG, testosterone (total and free)
  • Male hormones: Testosterone (total, free, bioavailable), dihydrotestosterone, free androgen index, estradiol, testosterone/estradiol ratio, SHBG, FSH, LH, prolactin
  • Prostate: PSA (total, free, percent free)
  • Growth and aging: IGF-1, DHEA-sulfate
Nutrients

Vitamins, minerals, iron and essential fats that power energy, methylation, immunity and repair.

  • Vitamins: Vitamin D (25-hydroxy), vitamin B12, folate (serum and RBC), methylmalonic acid, vitamin A, vitamin E, vitamin B1, vitamin B6, vitamin C, vitamin K1, coenzyme Q10
  • Minerals: RBC magnesium, zinc, copper, selenium, ceruloplasmin, iodine
  • Iron: Serum iron, total iron binding capacity, iron saturation, ferritin, transferrin
  • Omega fatty acids: Omega-3 index, EPA, DHA, DPA, total omega-6, arachidonic acid, linoleic acid, AA/EPA ratio, omega-6/omega-3 ratio (OmegaCheck)
Organ Function

Kidney, liver and pancreas health, with the electrolytes that keep them in balance.

  • Kidney: Creatinine, cystatin C, eGFR, blood urea nitrogen, BUN/creatinine ratio, urine albumin/creatinine ratio, phosphorus
  • Liver: ALT, AST, alkaline phosphatase, GGT, bilirubin (total, direct, indirect), LDH, total protein, albumin, globulin, albumin/globulin ratio
  • Pancreas: Amylase, lipase
  • Electrolytes: Sodium, potassium, chloride, carbon dioxide, calcium
Blood & Immune Health

Oxygen delivery, anemia, immune status and infection.

  • Red cells: RBC, hemoglobin, hematocrit, red cell indices (MCV, MCH, MCHC, RDW), reticulocytes
  • White cells: WBC with differential: neutrophils, lymphocytes, monocytes, eosinophils, basophils
  • Platelets: Platelet count, mean platelet volume
  • Immune ratios: Neutrophil/lymphocyte, platelet/lymphocyte and lymphocyte/monocyte ratios, systemic immune inflammation index
  • Blood type: ABO group and Rh type
Inflammation & Autoimmunity

Systemic inflammation and early signs of immune activity against the body's own tissues.

  • Inflammation: hs-CRP, sedimentation rate, interleukin-6, ferritin
  • Autoimmune screening: ANA with titer and pattern, rheumatoid factor, cyclic citrullinated peptide (CCP) antibody, complement C3 and C4
  • Gluten related: Tissue transglutaminase IgA, total IgA
  • Allergy: Total IgE
Heavy Metals

Blood levels of the most common toxic metals.

  • Metals: Lead, mercury, arsenic, cadmium
Urinalysis

Kidney, bladder and metabolic screening from a single urine sample.

  • Chemistry: Specific gravity, pH, glucose, protein, albumin, ketones, bilirubin, urobilinogen, blood, leukocyte esterase, nitrite
  • Microscopic exam: White and red blood cells, epithelial cells, casts, crystals, bacteria, yeast
Available as Indicated

Additional testing ordered when your history calls for it.

  • Viral Reactivation: Epstein Barr virus (VCA, early antigen, EBNA), cytomegalovirus and HHV-6 antibodies
  • Mold and Biotoxin Markers: TGF-β1, C4a, MMP-9, alpha MSH, VIP, VEGF, ADH and osmolality
  • Brain Health: AD-Detect amyloid beta 42/40 ratio and p-tau217
  • Allergy: IgE panels for foods, pollens, molds, dust and animals
  • Celiac Complete: Deamidated gliadin peptide IgA and IgG, endomysial antibody, HLA-DQ2/DQ8
  • Infectious Screening: Hepatitis B and C, HIV and others as clinically indicated
02

Genetics

Genes shape how each person absorbs, metabolizes and responds to medication. Pharmacogenetic testing identifies these variations so prescriptions can be tailored to the individual, reducing trial and error and helping avoid medications likely to cause side effects or fall short.

What We Evaluate

  • Response to more than 700 medications
  • Medications for depression, anxiety, ADHD and bipolar disorder
  • Pain medication selection
  • Medications that have failed or caused side effects
  • Safer prescribing when taking multiple medications
  • Planning a new prescription

Laboratories

Genomind
Genomind

Pharmacogenetic (PGx) Test

Cheek swab

A painless cheek swab assessing 26 genes that influence response to over 700 medications, with in depth insight into more than 130 neuropsychiatric medications.

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GenomindPharmacogenetic (PGx) Test

Genomind helps patients and providers tailor medications based on one's unique genetics, lifestyle and environment.

Genes Analyzed

How a medication acts on the body, and how the body processes it.

  • Pharmacodynamic: 15 genes
  • Pharmacokinetic: 11 genes
  • Medications assessed: More than 700, including over 130 neuropsychiatric medications
Collection and Results

Simple, painless and fast.

  • Sample: Cheek swab
  • Turnaround: 3 to 5 days
  • Accuracy: 99.9% laboratory accuracy
Report Options

Four formats for different clinical needs.

  • Express Report: A concise summary of medications to avoid, with suggested alternatives based on the patient's gene and drug interaction profile
  • NeuroPsych Report: A comprehensive five section report analyzing 26 genes, offering insights into 130+ neuropsychiatric medications
  • Diagnosis Report: Genetic results organized visually by clinical diagnosis, designed for fast interpretation
  • Patient Report: An easy to understand summary of genetic insights and medication recommendations
03

Environmental Toxins, Mycotoxins & Heavy Metals

Everyday exposure to metals, mold toxins, pesticides, plastics, solvents and industrial chemicals accumulates over time. A complete evaluation measures what the body is carrying, what the home or workplace contains, and how the immune system and cellular energy are responding.

What We Evaluate

  • Heavy metals in urine, hair and blood
  • Pesticides, herbicides and glyphosate
  • Plastics: phthalates, parabens and bisphenols
  • PFAS, solvents and volatile organic compounds
  • Mold toxins carried in the body
  • Molds and mycotoxins in the home or workplace
  • Biotoxin illness and CIRS inflammatory markers
  • Water damaged building exposure
  • Chemical sensitivity and mast cell activation

Laboratories

US BioTek
US BioTek

Toxin Panels and Combination Profiles

Urine

Urine panels for heavy metals and minerals (42 analytes), environmental toxins (48 metabolites) and glyphosate, available individually or combined with mycotoxin and organic acid testing.

US BioTek
RealTime Laboratories, now part of US BioTek

MycoToxin Panel and Building Profiles

Urine and dust swab

Urine testing for 16 of the most common mycotoxins across 5 mycotoxin families, with dust swab testing of the home or workplace for toxigenic molds and mycotoxins.

Doctor's Data
Doctor's Data

Hair Elements

Hair, 0.25 grams

More than 40 toxic and essential elements, reflecting recent and ongoing exposure to toxic metals, especially methylmercury and arsenic, and the time averaged status of nutrient elements.

Quest Diagnostics
Quest Diagnostics

Biotoxin Markers and Blood Metals

Blood draw

Blood markers of the immune and hormonal response to biotoxins, and whole blood levels of lead, mercury, arsenic and cadmium.

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Heavy Metals
Urine Heavy Metals & Minerals Panel

US BioTek. 42 toxic and essential elements.

  • Element classes: Transition metals, post transition metals, non metal elements, metalloids, alkali metals, alkaline earth metals, halides (halogens), lanthanoids
Hair Elements

Doctor's Data. Recent and ongoing exposure, especially methylmercury and arsenic, and time averaged nutrient status.

  • Toxic metals: Arsenic, mercury, lead, cadmium, aluminum, antimony and others
  • Essential elements: Magnesium, zinc, selenium, chromium, copper, iron and others
  • Exposure: Toxic element exposure, high fish intake
  • Symptoms: Hair loss, depression, fatigue, neurological symptoms, sexual dysfunction, vision concerns
  • Physiology: Malabsorption, kidney function, hypertension, glucose tolerance
Blood Metals

Quest Diagnostics. Whole blood levels.

  • Metals: Lead, mercury, arsenic, cadmium
Environmental Chemicals
Environmental Toxins Panel

US BioTek. 48 metabolites of common environmental chemicals.

  • Chemical classes: Environmental phenols, herbicides, pesticides, parabens, phthalates, volatile organic compounds, PFAS, cysteine derivatives, other environmental pollutants
  • Cellular impact: Mitochondrial markers
Glyphosate

US BioTek. The most widely used herbicide.

  • Test: Urinary glyphosate
Mycotoxins & Mold
Body Profile

RealTime Laboratories. What the body is currently carrying.

  • MycoToxin Panel: 16 of the most common mycotoxins produced by 5 mycotoxin families, including aflatoxins, ochratoxins, trichothecenes, gliotoxins and zearalenone. Urine test
Building Profiles

What the home or workplace contains, by dust swab.

  • Mold and Mycotoxin Building Profile: 15 toxigenic molds and 16 mycotoxins for a comprehensive evaluation of a building
  • Mold Building Profile: 15 toxigenic molds
  • Mycotoxin Building Profile: 16 of the most toxic mycotoxins
Body and Building Combined

The complete picture of exposure and toxic load.

  • Comprehensive Body and Building Profile: 44 urinary mycotoxin metabolites, environmental molds and environmental mycotoxins. Includes the Mold and Mycotoxin Building Profile and MycoToxin Panel
Biotoxin Inflammatory Markers
Immune Response

Quest Diagnostics. Innate immune activation driven by biotoxins.

  • Markers: TGF-β1, C4a, MMP-9, VEGF
Neuroendocrine Response

Hormonal regulation commonly disrupted in CIRS.

  • Markers: Alpha MSH, VIP, ADH and osmolality, ACTH and cortisol, leptin
Genetic Susceptibility

Inherited ability to clear biotoxins.

  • Marker: HLA-DR / DQ
Combination Profiles
Toxin and Organic Acid Profiles

US BioTek. Broader workups in a single urine collection.

  • All-Tox Profile: A broad workup of environmental toxins, heavy metals and mycotoxins, along with glyphosate. Heavy Metals + MycoToxin Panel + Environmental Toxins + Glyphosate
  • MOE-Tox Profile: Evaluates toxicity together with organic acids. MycoToxin Panel + 62 Organic Acids + Environmental Toxins
  • MOE-Tox Complete Profile: The most comprehensive look at heavy metals, environmental toxins and mycotoxins combined with the 62 Organic Acids, for a complete study of toxic burden and mitochondrial function
04

Nutrients & Micronutrients

Every enzyme, hormone and neurotransmitter depends on nutrients. Functional nutrient testing measures what the body actually needs, pairing blood and urine markers to identify deficiencies, imbalances and increased demand long before they surface as disease.

What We Evaluate

  • Functional need for 40 vitamins, minerals and antioxidants
  • Amino acids and essential fatty acids
  • Oxidative stress and antioxidant reserve
  • Fatigue, mood and weight concerns
  • Maldigestion and malabsorption
  • Restrictive and plant based diets
  • Athletic performance, recovery and healing

Laboratories

Genova Diagnostics
Genova Diagnostics

NutrEval FMV

Blood and first morning urine

Evaluates over 125 biomarkers and the body's functional need for 40 antioxidants, vitamins, minerals, essential fatty acids, amino acids, digestive support and other select nutrients.

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Genova DiagnosticsNutrEval FMV

NutrEval is both a blood and urine profile that evaluates over 125 biomarkers and assesses the body's functional need for 40 antioxidants, vitamins, minerals, essential fatty acids, amino acids, digestive support and other select nutrients.

Organic Acids

Urinary markers of how nutrients are being used.

  • Areas: Malabsorption and dysbiosis, cellular energy and mitochondria, neurotransmitter metabolism, vitamin markers, toxin and detoxification markers
Amino Acids

Building blocks for protein, neurotransmitters and detoxification.

  • Measured: Essential and nonessential amino acids, plasma or urine
Essential & Metabolic Fatty Acids

Fats that shape inflammation, membranes and brain health.

  • Measured: Omega-3, omega-6, omega-9, saturated and trans fats, in red blood cells
Oxidative Stress

Antioxidant reserve and cellular damage.

  • Measured: Glutathione, lipid peroxides, 8-OHdG, coenzyme Q10
Elemental Markers

Nutrient minerals and toxic metals.

  • Nutrient elements: Magnesium, zinc, copper, selenium, manganese, potassium and others
  • Toxic elements: Lead, mercury, arsenic, cadmium
Add Ons
  • Vitamin D: Serum
  • Nutrient related SNPs: Cheek swab
Commonly Used For
  • Conditions: Mood disorders, cardiovascular disease, obesity, insulin resistance and type 2 diabetes, fatigue, weight and dietary guidance, malnutrition, maldigestion and malabsorption, athletic performance, physical trauma and healing
05

Hormones & Metabolic Function

Hormones and metabolism work as one system. Sex and adrenal hormones govern energy, mood, sleep, weight, libido and cycles, while cellular metabolism determines how well the body produces energy, uses nutrients and clears toxins. Measuring both, side by side, shows where balance has been lost and why.

What We Evaluate

  • Estrogen, progesterone and testosterone with their metabolites
  • Estrogen detoxification pathways
  • Daily cortisol rhythm, DHEA and overnight melatonin
  • Perimenopause, menopause, PMS and irregular cycles
  • PCOS, low testosterone and low libido
  • Adrenal fatigue and burnout
  • Mitochondrial energy production
  • Vitamin, cofactor and methylation markers
  • Yeast and bacterial overgrowth
  • Detoxification and oxidative stress

Laboratories

DUTCH
Precision Analytical (DUTCH)

DUTCH Complete

Dried urine, four collections over 24 hours

A complete evaluation of sex and adrenal hormones and their metabolites, the daily cortisol rhythm, overnight melatonin, and markers of oxidative stress and micronutrient status.

US BioTek
US BioTek

62 Organic Acids Profile

Urine

A comprehensive workup of overall metabolic health, with markers of energy production, detoxification, bacterial and yeast dysbiosis, methylation, neurotransmitter metabolism and nutrition.

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Precision Analytical (DUTCH)DUTCH Complete

DUTCH is a group of validated tests that provide a complete evaluation of sex and adrenal hormones, including metabolites. The DUTCH Complete analyzes 35 hormones and metabolites. Dried samples are stable for several weeks, making home collection convenient.

Estrogens

Production and the pathways by which estrogen is cleared.

  • Hormones: Estrone, estradiol, estriol
  • Metabolism: 2-OH, 4-OH and 16-OH estrogens, methylation activity
Progesterone

Production and metabolism.

  • Metabolites: Alpha and beta pregnanediol
Androgens

Testosterone and its metabolites.

  • Markers: Testosterone, epitestosterone, DHT, androsterone, etiocholanolone, 5 alpha and 5 beta androstanediol
Adrenal

Cortisol production and its rhythm across the day.

  • Markers: Free cortisol and cortisone at four times of day, metabolized cortisol, DHEA-S
Organic Acids

Nutrient, neurotransmitter and oxidative stress markers.

  • Markers: Melatonin (6-OHMS), 8-OHdG, vitamin B12 (methylmalonate), vitamin B6 (xanthurenate), kynurenate, glutathione (pyroglutamate), dopamine (homovanillate), norepinephrine and epinephrine (vanilmandelate)
Commonly Used For
  • Symptoms: Fatigue, weight gain, hair loss, mood swings
Other DUTCH Tests
  • DUTCH Plus: Everything in the DUTCH Complete plus the Cortisol Awakening Response, for a deeper look at stress and adrenal function
  • Cycle Mapping: Tracks hormone patterns across the menstrual cycle
US BioTek62 Organic Acids Profile

The US BioTek Organic Acids Profile delivers a comprehensive workup of overall metabolic health, with markers in glycolysis, detoxification indicators, bacterial and yeast dysbiosis markers, methylation cofactors, neurotransmitter metabolism and nutritional markers.

Gut Microbial Markers

Byproducts of bacteria and yeast in the gut.

  • Categories: Microbial overgrowth, yeast and fungal metabolites
Energy & Mitochondria

How efficiently cells turn food into energy.

  • Categories: Mitochondrial and energy metabolism, carbohydrate and glycemic metabolism, fatty acid oxidation and ketone metabolism
Nutrient Cofactors

Functional need for vitamins and amino acids.

  • Categories: Vitamin and nutritional cofactor markers, pyrimidine metabolites (folate metabolism), amino acid and branched chain metabolism
Brain & Stress

Neurotransmitter turnover and the stress response.

  • Categories: Neurotransmitter metabolites, adrenal stress (overnight), tryptophan and kynurenine pathway
Detoxification & Oxidative Stress

Clearance capacity and cellular protection.

  • Categories: Detoxification and glutathione function, oxidative stress and inflammation, oxalate metabolism, environmental and xenobiotic exposure
Reference
  • Marker: Creatinine
06

Brain Health, Cognition & Neurotransmitters

Mood, focus, memory and sleep depend on the chemistry and health of the nervous system. Neurotransmitter testing shows how the body makes and breaks down its chemical messengers, while cognitive health testing brings together genetic risk, blood biomarkers and immune reactivity to neurological tissue, often years before changes are noticed.

What We Evaluate

  • Serotonin, dopamine, GABA, glutamate and the catecholamines
  • Depression, anxiety, insomnia and low drive
  • Brain fog, inattention and forgetfulness
  • Cravings, obsessions, addiction and dependency
  • APOE genotype and Alzheimer's blood biomarkers
  • Memory changes and family history of Alzheimer's
  • Neuroinflammation and neurological autoimmunity
  • Recovery after concussion and brain injury

Laboratories

Doctor's Data
Doctor's Data

Neurotransmitter Profile

Urine

A urine assessment of the body's ability to make and break down neurotransmitters, including serotonin, dopamine, GABA, glutamate and the catecholamines, representative of whole body levels.

Quest Diagnostics
Quest Diagnostics

Brain Health Blood Markers

Blood draw

APOE genotyping and Alzheimer's blood biomarkers, alongside the nutrient and vascular markers most tied to cognitive health.

Cyrex Laboratories
Cyrex LaboratoriesComing Soon

Neurological Immune Arrays

Blood draw

Multi tissue antibody testing for immune reactivity linked to neurodegeneration, neurological autoimmunity and blood brain barrier permeability.

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Doctor's DataNeurotransmitter Profile

Urinary neurotransmitter levels provide an overall assessment of the body's ability to make and break down neurotransmitters and are representative of whole body levels. Abnormal levels may be associated with cognitive and mood concerns, diminished drive, fatigue, sleep difficulties, cravings, addictions, pain, and abnormal abundance and diversity within the gastrointestinal microbiome.

Catecholamines

Drive, focus, motivation and the stress response.

  • Free: Dopamine, norepinephrine, epinephrine, norepinephrine/epinephrine ratio
  • Metabolites: DOPAC, 3-methoxytyramine, metanephrine, normetanephrine
Serotonin Pathway

Mood, sleep and gut motility.

  • Markers: Serotonin, 5-hydroxyindoleacetic acid (5-HIAA)
Amino Acid Neurotransmitters

The balance of calming and stimulating signals.

  • Markers: GABA, glutamate, glycine, taurine
Trace Amines & Precursors
  • Markers: Histamine, phenethylamine (PEA), tryptamine, tyramine, tyrosine
Reference
  • Marker: Creatinine
Quest DiagnosticsBrain Health Blood Markers
Genetic Risk
  • Marker: Apolipoprotein E (APOE) genotype
Alzheimer's Blood Biomarkers

Blood markers of amyloid and tau.

  • Markers: AD-Detect amyloid beta 42/40 ratio, AD-Detect p-tau217
Nutrient & Vascular

Modifiable factors tied to cognitive health.

  • Markers: Homocysteine, vitamin B12, methylmalonic acid, vitamin D, omega-3 index, hemoglobin A1c, fasting insulin
Cyrex LaboratoriesNeurological Immune ArraysComing Soon
Arrays
  • Alzheimer's LINX: Alzheimer's associated immune reactivity
  • Array 7X: Neurological Autoimmune Reactivity Screen, Expanded
  • Array 20: Blood Brain Barrier Permeability
07

Gut & Digestive Health

The gut influences digestion, immunity, inflammation, mood and detoxification. A comprehensive stool analysis shows how well food is broken down and absorbed, whether the gut lining is inflamed and which organisms make up the microbiome, while breath testing reveals bacterial overgrowth in the small intestine.

What We Evaluate

  • Digestion and absorption
  • Gut inflammation and immune markers
  • Microbiome composition and function
  • Bacterial and fungal cultures with sensitivities
  • Parasites, H. pylori and C. difficile
  • SIBO and methane overgrowth by breath test
  • IBS, bloating, constipation and diarrhea
  • Intestinal permeability
  • Inflammatory bowel disease monitoring

Laboratories

Genova Diagnostics
Genova Diagnostics

GI Effects Comprehensive Stool Profile

Stool

A comprehensive stool analysis of the three key functions of gut health: Digestion and Absorption, Inflammation and Immunology, and the Gut Microbiome, with full parasitology on every exam.

Genova Diagnostics
Genova Diagnostics

SIBO Breath Test

Breath, collected at home

Hydrogen and methane breath testing to evaluate small intestinal bacterial overgrowth and intestinal methanogen overgrowth, in 2 or 3 hour options.

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Genova DiagnosticsGI Effects Comprehensive Stool Profile

The biomarkers on the GI Effects Comprehensive Profile reflect the three key functions of gut health, arranged in the "DIG" format: Digestion/Absorption, Inflammation/Immunology and the Gut Microbiome.

Digestion & Absorption

How well food is broken down and absorbed.

  • Markers: Pancreatic elastase-1, products of protein breakdown, fecal fat
Inflammation & Immunology

The state of the gut lining and its immune defenses.

  • Markers: Calprotectin, eosinophil protein X, fecal secretory IgA, fecal occult blood
Gut Microbiome

Composition, abundance and function of gut organisms.

  • Metabolic indicators: Short chain fatty acids and beta-glucuronidase, demonstrating vital metabolic functions performed by the microbiota
  • Commensal bacteria: 24 genera and species mapping to 7 major phyla by 16S rRNA gene qPCR, with comprehensive microbiome analysis
  • Cultures: Bacterial and mycology cultures identified by MALDI-TOF mass spectrometry
  • Sensitivities: Prescriptive and natural agents effective against pathogenic or potentially pathogenic organisms cultured
Parasitology

Comprehensive testing for all parasites on every exam.

  • Microscopy: Ova and parasites (O&P), the gold standard for many parasites
  • PCR: Blastocystis spp., Cryptosporidium parvum/hominis, Cyclospora cayetanensis, Dientamoeba fragilis, Entamoeba histolytica, Giardia
Add On Biomarkers
  • Markers: Campylobacter, Clostridium difficile, Shiga toxin E. coli, Helicobacter pylori, fecal lactoferrin, macroscopic exam for worms, zonulin family peptide, KOH preparation for yeast
Add On Modules
  • Microbiomix: Metagenomic shotgun (whole genome) sequencing of the complete gut microbiome and its potential function
  • IgG Food Antibodies: 87 foods, bloodspot
  • Parasitology Module: Direct examination for parasites
Genova DiagnosticsSIBO Breath Test
Gases Measured

Fermentation gases produced by bacteria in the small intestine.

  • Gases: Hydrogen and methane
Conditions Assessed
  • SIBO: Small intestinal bacterial overgrowth
  • IMO: Intestinal methanogen overgrowth
Test Options
  • Substrate: Lactulose
  • Duration: 2 hour or 3 hour assessment; 3 hour recommended with slower transit or constipation
  • Collection: Noninvasive breath samples collected at home
08

Autoimmunity & Food Reactivity

Autoimmune disease often begins years before diagnosis, as the immune system reacts to foods, gut barrier breakdown and the body's own tissues. Measuring these antibodies early reveals where the immune system is under strain and which foods may be fueling it.

What We Evaluate

  • Food sensitivity to 96, 144 or 240 foods
  • Wheat, gluten and cross reactive foods
  • Intestinal permeability
  • Multiple tissue autoimmune antibodies
  • Hashimoto's, celiac, rheumatoid arthritis and lupus
  • Eczema, hives, migraines and joint pain

Laboratories

US BioTek
US BioTek

Food Sensitivity Panels

Dried blood spot

IgG, IgG4 and IgA reactivity to 96, 144 or 240 foods, with specialized vegetarian and regional diet panels and optional complement (C3d) testing.

Cyrex Laboratories
Cyrex LaboratoriesComing Soon

Cyrex Arrays

Blood draw

Multi tissue antibody testing for the early detection and monitoring of complex autoimmune conditions, intestinal permeability, gluten reactivity and food immune reactivity.

View full test details
US BioTekFood Sensitivity Panels
Standard Panels

IgG, IgG4 and IgA reactions.

  • 96 Foods: Essential foods
  • 144 Foods: Broader evaluation
  • 240 Foods: For complex cases
Specialized Diet Panels
  • Regional: 96 Asian, 96 Japanese, 96 Mexican
  • Vegetarian: 96 and 198 vegetarian foods
Add On
  • C3d: A stable marker of complement activation, identifying inflammatory food sensitivity reactions
Cyrex LaboratoriesCyrex ArraysComing Soon

Cyrex is a clinical immunology laboratory specializing in functional immunology and autoimmunity, offering multi tissue antibody testing for the early detection and monitoring of today's complex autoimmune conditions.

Gut Barrier & Digestion
  • Array 2: Intestinal Antigenic Permeability Screen
  • Array 14: Mucosal Immune Reactivity Screen
  • Array 22: Irritable Bowel / SIBO Screen
Gluten & Food
  • Array 3X, WheatBurden: Wheat, Gluten and Processed Protein Forms
  • Array 4: Gluten Associated Cross Reactive Foods and Foods Sensitivity
  • Array 10 and 10-90: Multiple Food Immune Reactivity Screen
Autoimmunity
  • Array 5: Multiple Autoimmune Reactivity Screen
Brain & Nervous System
  • Array 7X: Neurological Autoimmune Reactivity Screen, Expanded
  • Array 20: Blood Brain Barrier Permeability
  • Alzheimer's LINX: Alzheimer's Associated Immune Reactivity
Chemical & Pathogen
  • Array 11: Chemical Immune Reactivity Screen
  • Array 12: Pathogen Associated Immune Reactivity Screen
Candida & Microbiome
  • BiomeBurden Complete: Myco, Micro and Immune Evaluation
  • Micro-BiomeBurden: Candida Virulence Plus
  • Myco-BiomeBurden: Candida Virulence
Immune Status
  • Total Serum IgG / IgA / IgM
  • The Lymphocyte MAP: Comprehensive Lymphocyte Immunophenotyping
09

Chronic & Tick Borne Infections

Lyme disease, its coinfections and reactivated viruses can drive fatigue, pain and neurological symptoms long after the original exposure. Specialized testing detects these hard to find organisms with greater sensitivity than standard screening.

What We Evaluate

  • Lyme disease by two tier testing and immunoblot
  • Babesia, Bartonella, Ehrlichia and Anaplasma
  • Tick borne relapsing fever and Rickettsia
  • Epstein Barr, CMV and HHV-6 reactivation
  • Post viral fatigue
  • Migratory joint pain and unexplained neurological symptoms

Laboratories

Quest Diagnostics
Quest Diagnostics

Infection and Viral Panels

Blood draw

Standard testing for Lyme disease, tick borne coinfections and reactivated viruses, available at any Quest location.

IGeneX
IGeneXComing Soon

Lyme & Tick Borne Disease Testing

Blood draw

A global leader in testing for Lyme disease, relapsing fever and other tick borne diseases, with over 30 years of experience and FDA cleared ImmunoBlots for early detection.

View full test details
Quest DiagnosticsInfection and Viral Panels
Lyme Disease

Two tier testing to current CDC standards.

  • Tests: Lyme disease antibody screen with reflex to immunoblot (IgG and IgM)
Tick Borne Coinfections
  • Tests: Babesia, Bartonella, Ehrlichia and Anaplasma antibodies and PCR
Viral Reactivation

Viruses that can reactivate and contribute to chronic fatigue.

  • Epstein Barr virus: VCA IgG and IgM, early antigen, nuclear antigen (EBNA)
  • Other: Cytomegalovirus and HHV-6 IgG and IgM
IGeneXLyme & Tick Borne Disease TestingComing Soon
Lyme Disease
  • Organism: Borrelia
  • Method: Lyme ImmunoBlots, including FDA cleared single step immunoblots
Relapsing Fever
  • Organism: Tick borne relapsing fever Borrelia
Coinfections
  • Organisms: Babesia, Bartonella, Ehrlichia, Anaplasma, Rickettsia
10

Healthy Aging & Longevity

Chronological age counts years; biological age measures how the body is actually aging. Epigenetic testing reveals the pace of aging across the body and within each organ system, and shows whether lifestyle and treatment are slowing it.

What We Evaluate

  • Biological age
  • Pace of aging
  • Ages of 11 organ systems
  • Immune cell profile
  • Response to lifestyle and treatment

Laboratories

TruDiagnostic
TruDiagnosticComing Soon

TruAge

Finger stick blood

Measures biological age through DNA methylation at more than 1,000,000 sites, reporting biological age, pace of aging and the ages of 11 organ systems.

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TruDiagnosticTruAgeComing Soon

TruAge measures biological age through DNA methylation analysis, the chemical tagging system cells use to regulate gene activity, across more than 1,000,000 sites.

Epigenetic Clocks
  • OMICmAge: Biological age
  • DunedinPACE: Speed of aging
  • SYMPHONYAge: Ages of 11 organ systems, including brain, heart, immune, liver, kidney and lung
Immune Profile
  • Immune cell deconvolution: Filters cellular noise for more precise aging insights
Collection
  • Method: Finger stick, about three minutes
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Advanced Imaging

Imaging shows structure directly: plaque in the arteries, density of bone, fat within the liver and muscle, and early changes in organs long before symptoms appear. Advanced preventive imaging and all routine imaging, including X-rays, ultrasound, CT and MRI, are arranged through SimonMed and read by board certified radiologists.

What We Evaluate

  • Whole body MRI for early detection
  • Coronary calcium score and plaque analysis
  • Bone density and body composition
  • Brain MRI with volumetrics
  • Liver fat and fibrosis
  • Thyroid, breast and prostate imaging
  • Routine X-ray, ultrasound, CT and MRI

Laboratories

SimonMed Imaging
SimonMed Imaging

Preventive and Diagnostic Imaging

SimonMed imaging center

Whole body MRI, cardiovascular imaging, bone density and body composition, brain volumetrics, and all routine imaging including X-rays, ultrasound, CT and MRI, read by board certified radiologists.

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SimonMed ImagingPreventive and Diagnostic Imaging
Longevity & Early Detection
  • Whole body MRI: Chest, abdomen and pelvis covering 13 major organs and 35 body structures, with optional head, neck and spine. May identify tumors, blood clots, aneurysms, signs of stroke, brain changes associated with Alzheimer's risk, and liver scarring or fatty liver
  • Enhanced Screening: Whole body MRI with 100+ biomarkers, body composition and AI powered reporting
  • Cancer screening: Lung CT, virtual CT colonoscopy
Cardiovascular
  • Imaging: Coronary calcium score, coronary CT angiogram (CCTA), CCTA with AI plaque analysis, CCTA with FFR, cardiac MRI, echocardiogram, MRA, CT angiogram
Bone, Muscle & Body Composition
  • Imaging: DEXA bone density, DEXA with trabecular bone score, DEXA body composition, advanced body composition MRI, Muscle by SpringBok, CT with bone density AI
Brain
  • Imaging: Brain MRI, NeuroQuant volumetrics, advanced TBI protocol, MR spectroscopy, PET/CT amyloid imaging, DaTscan
Liver & Digestive
  • Imaging: Liver Multi Scan, elastography, MR enterography, ultrasound, HIDA scan, gastric emptying study
Thyroid & Endocrine
  • Imaging: Thyroid ultrasound, parathyroid scan
Women's Health
  • Imaging: 3D mammogram, Mammogram+, Mammogram+ Heart, breast ultrasound, breast MRI, pelvic and OB ultrasound
Men's Health
  • Imaging: Prostate MRI, PSMA PET/CT
Musculoskeletal
  • Imaging: MSK and sports MRI, lumbar spine MRI, X-ray
Standard Imaging

The full range of routine diagnostic imaging, ordered as clinically indicated.

  • Available: X-rays, ultrasound of any region, CT and MRI of any body area, fluoroscopy and barium studies, nuclear medicine studies, and image guided biopsy
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Sleep

Coming Soon